History: American Old West, United States

The principal commercial goal was to find an efficient route to connect American goods and natural resources with Asian markets, and perhaps to find a means of blocking the growth of British fur trading companies into the Oregon Country. Asian merchants were already buying sea otter pelts from Pacific coast traders for Chinese customers. An expansion of inland fur trading was also anticipated. With news spreading of the expedition's findings, entrepreneurs like John Jacob Astor immediately seized the opportunity and expanded fur trading operations into the Pacific Northwest. Astor's "Fort Astoria" (later Fort George), at the mouth of the Columbia River, became the first permanent white settlement in that area. However, during the War of 1812, the rival North West Company (a British-Canadian company) bought the camp from Astor's agents as they feared the British would destroy an American camp. For a while, Astor's fur business suffered. But he rebounded by 1820, took over independent traders to create a powerful monopoly, and left the business as a multi-millionaire in 1834, reinvesting his money in Manhattan real estate.
• Fur trade
The quest for furs was the primary commercial reason for the exploration and colonizing of North America by the Dutch, French, and British. The Hudson's Bay Company, promoting British interests, often competed with French traders who had arrived earlier and had been already trading with indigenous tribes in the northern border region of the colonies. This competition was one of the contributing factors to the French and Indian War in 1763. British victory in the war led to the expulsion of the French from the American colonies. French trading continued, however, based in Montreal. Astor's move into the Northwest was a major American attempt to eat with the established French and English traders.
As the frontier moved westward, trappers and hunters moved ahead of settlers, searching out new supplies of beaver and other skins for shipment to Europe. The hunters proceeded and followed Lewis and Clark to the Upper Missouri and the Oregon territory; they formed the first working relationships with the Native Americans in the West. They also added extensive knowledge of the Northwest terrain, including the important South Pass through the central Rocky Mountains. Discovered about 1812, it later became a major route for settlers to Oregon and Washington.