History: New York City, 1978, United States

Midtown Manhattan is the largest central business district in the United States. Lower Manhattan is the third largest central business district in the United States, and is home to The New York Stock Exchange, located on Wall Street, and the NASDAQ, representing the world's first and second largest stock exchanges, respectively, when measured by average daily trading volume and overall market capitalization. Financial services account for more than 35% of the city's employment income.
Real estate is a major force in the city's economy, as the total value of all New York City property was $802.4 billion in 2006. The Time Warner Center is the property with the highest-listed market value in the city, at $1.1 billion in 2006. New York City is home to some of the nation's—and the world's—most valuable real estate. 450 Park Avenue was sold on July 2, 2007 for $510 million, about $1,589 per square foot ($17,104/m²), breaking the barely month-old record for an American office building of $1,476 per square foot ($15,887/m²) set in the June 2007 sale of 660 Madison Avenue.
The city's television and film industry is the second largest in the country after Hollywood. Creative industries such as new media, advertising, fashion, design and architecture account for a growing share of employment, with New York City possessing a strong competitive advantage in these industries.
High-tech industries like biotechnology, software development, game design, and internet services are also growing, bolstered by the city's position at the terminus of several transatlantic fiber optic trunk lines. Other important sectors include medical research and technology, non-profit institutions, and universities.